2024
- Jackson, H. D., Cotler, M. J., Saunders, G. W., Cornelssen, C. A., West, P. J., Metcalf, C. S., Wilcox, K. S., & Cima, M. J. (2024). Intracerebral delivery of antiseizure medications by microinvasive neural implants. Brain: A Journal of Neurology, awae282. https://doi.org/10.1093/brain/awae282
- Sherman SE, Zammit AS, Heo WS, Rosen MS, Cima MJ. Single-sided magnetic resonance-based sensor for point-of-care evaluation of muscle. Nat Commun. 2024 Jan 10;15(1):440. doi: 10.1038/s41467-023-44561-9. PMID: 38199994; PMCID: PMC10782019.
2023
- Erin Rousseau, Ritu Raman, Tigist Tamir, Angel Bu, Shriya Srinivasan, Naomi Lynch, Robert Langer, Forest M. White, Michael J. Cima, Actuated tissue engineered muscle grafts restore functional mobility after volumetric muscle loss, Biomaterials, 2023, ISSN 0142-9612
- Xia M, Agca BN, Yoshida T, Choi J, Amjad U, Bose K, Keren N, Zukerman S, Cima MJ, Graybiel AM, Schwerdt HN, Scalable, flexible carbon fiber electrode thread arrays for three-dimensional spatial profiling of neurochemical activity in deep brain structures of rodents, bioRxiv 2023 Apr
- Cormack R, Tokuda J, Ekchian G, Kaza E, Dyer M, Cima MJ Oxygen sensitivity of a silicone based magnetic resonance contrast agent; Elsevier 2023 May
2022
- Cotler MJ, Ramadi KB, Hou X, Christodoulopoulos E, Ahn S, Bashyam A, Ding H, Larson M, Oberg AL, Whittaker C, Jonas O, Kaufmann SH, Weroha SJ, Cima MJ, Machine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors, Transl Oncol 2022 Jul, Epub 2022 Apr 26.
2021
- Cormack R, Tokuda J, Ekchian G, Cima MJ, Lee, L Feasbility Study of Quantitative Silicone Oxygen sensors in HDR Cervical Cancer Brachytherapy, Elsevier 2021 May
- Schwerdt, H, Gibson DJ, Kenichi A, Stanwicks, LL, Yoshida T, Cima MJ, Graybiel AM Chronic multi-modual monitoring of neural activity in rodents and primates; SPIE 2021 March
2020
- Bashyam A, Frangieh C, Sogo J, Bronson RT, Uygun K, Yeh H, Ausiello DA, Cima MJ, A portable single-sided magnetic-resonance sensor for the grading of liver steatosis and fibrosis, Nature Biomedical Eng. (2020 Nov 30)
- Rousseau R, Raman R, Wade M, Tong A, Cotler MJ, Kuang J, Lugo AA, Zhang E, Graybiel AM, White FM, Langer R, Cima MJ, Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid, Sci Adv. (2020 Sept 25)
- Ramadi KB, Bashyam A, Frangieh CJ, Rousseau EB, Cotler MJ, Langer R, Graybiel AM, Cima MJ, Computationally Guided Intracerebral Drug Delivery via Chronically Implanted Microdevices, Cell Rep (2020 June 9)
2019
- Bhagavatula SK, Upadhyaya K, Miller BJ, Bursch P, Lammers A, Cima MJ, Silverman SG, Jonas O, An interventional image-guided microdevice implantation and retrieval method for in-vivo drug response assessment, Med Phys (2019 Nov)
- Cotler MJ, Rousseau EB, Ramadi KB, Fang J, Graybiel AM, Cima MJ, Langer R, Steerable Microinvasive Probes for Localized Drug Delivery to Deep Tissue, Small (2019 Sept 15)
2018
- A. Bashyam, M. Li, M.J. Cima, Design and experimental validation of Unilateral Linear Halbach magnet arrays for single-sided magnetic resonance, J. Magn. Reson. 292 (2018).
- Dagdeviren, C., K. B. Ramadi, P. Joe, K. Spencer, H. N. Schwerdt, H. Shimazu, S. Delcasso, K. Amemori, C. Nunez Lopez, A. M. Graybiel, M. J. Cima and R. Langer. “Miniaturized Neural System for Chronic, Local Intracerebral Drug Delivery.” Science Translational Medicine, Jan. 2018.
2017
- H.N. Schwerdt, H. Shimazu, K. Amemori, S. Amemori, P.L. Tierney, D.J. Gibson, S. Hong, T. Yoshida, R. Langer, M.J. Cima, and A.M. Graybiel, “Long-term dopamine neurochemical monitoring in primates,” Proceedings of the National Academy of Sciences, vol. 114, no. 50, pp. 13260–13265, Nov. 2017.
- Spencer, K. C., J. C. Sy, K. B. Ramadi, A. M. Graybiel, R. Langer and M. J. Cima. “Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.” Sci Rep 7(1): 1952, May 2017.
- H.N. Schwerdt, M.J. Kim, S. Amemori, D. Homma, T. Yoshida, H. Shimazu, H. Yerramreddy, E. Karasan, R. Langer, A.M. Graybiel, and M. J. Cima, “Subcellular probes for neurochemical recording from multiple brain sites,” Lab Chip, vol. 17, no. 6, pp. 1104–1115, March 2017. PubMed PMID: 28233001
- Spencer, K. C., J. C. Sy, R. Falcon-Banchs and M. J. Cima. “A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants.” Lab Chip 17(5): 795-804, Jan. 2017.
2015
- Li, M., Vassiliou, C.C., Colucci, L.A., Cima, M.J. 1H nuclear magnetic resonance (NMR) as a tool to measure dehydration in mice. NMR in Biomedicine, Aug 2015, Vol. 28, Issue 8, p1031-1039. ISSN: 09523480
- Li, M., Cima, M.J., Milner Jr., D.A. If It’s Not One Thing, It’s Another: An Inverse Relationship of Malignancy and Atherosclerotic Disease. PLoS ONE, May 2015, Vol. 10 (5), p1-12. DOI: 10.1371/journal.pone.0126855
- C. C. Vassiliou, V. H. Liu, M. J. Cima, Miniaturized, biopsy-implantable chemical sensor with wireless, magnetic resonance readout, Lab on a Chip, 2015, DOI: 10.1039/C5LC00546A
2014
- Tavassolian N, Li M, Vassilou CC, Cima MJ, A Novel Magnetic Relaxation-Based Platform for Hydration Monitoring, IEEE Sensors Journal, 2014.
- Liu VH, Vassiliou CC, Imaad SM, and Cima MJ; Solid MRI contrast agents for long-term, quantitative in vivo oxygen sensing, to be published Proceedings of the National Academy of Sciences, Volume 111, Number 18. (2014)
- Cima MJ, Lee H, Daniel K, Tanenbaum LM, Mantzavinou A, Spencer KC, Ong Q, Sy JC, Santini J Jr, Schoellhammer CM, Blankschtein D, Langer RS. Single compartment drug delivery. Journal of Controlled Release. 2014;190:157-71. PMID: 24798478, PMCID: PMC4179298.
2013
- Upadhyay, U.M., Tyler, B., Patta, Y., Wicks R., Spencer, K., Scott, A., Masi, B., Hwang, L., Grossman, R., Cima, M., Brem, H., Langer, R. Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. Proc Natl Acad Sci. 2013; 11(45):16071-76. DOI: 10.1073/pnas.1313420110
2012
- Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ. Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. Biomaterials. 2012;33(23):5768-75. PMID: 22591609, PMCID: pending
- Farra R, Sheppard NF, Jr., McCabe L, Neer RM, Anderson JM, Santini JT, Jr., Cima MJ, Langer R. First-in-human testing of a wirelessly controlled drug delivery microchip. Science translational medicine. 2012;4(122):122ra21. PMID: 22344516, PMCID: pending
2011
- Y. Ling, M.J. Cima, Implantable Magnetic Relaxation Sensors for the Detection of Cardiac Biomarkers, Nature Biotechnology. 2011;29(3):273-7. PMID: 21317907, PMCID: pending
- Scott, A. W., Tyler, B. M., Masi, B. C., Upadhyay, U. M., Patta, Y. R., Grossman, R., Basaldella, L., Langer, R. S., Brem, H. & Cima, M. J., Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials. 2011;32(10):2532-9. PMID: 21220172, PMCID: pending
- Cima, M. J. (2011). “Microsystem Technologies for Medical Applications.” Annual Review of Chemical and Biomolecular Engineering 2(1): 355-378. PMID: 22432623, PMCID: pending
- Ling, Y., et al (2011) Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers. Nature Biotechnology, Article in Press.
- Lee, H., Cima, M.J., (2011) An intravesical device for the sustained delivery of lidocaine to the bladder. Journal of Controlled Release, 149 (2), pp. 133-139.
- Scott, A.W., et al (2011) Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials, 2011.
2010
- Lee, H. & Cima, M. J., An intravesical device for the sustained delivery of lidocaine to the bladder. Journal of Controlled Release. 2010;149(2):133-9. PMID: 20971144, PMCID: pending
- Elman, N. M., Masi, B. C., Cima, M. J. & Langer, R., Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical-Systems. Lab on a Chip – Miniaturisation for Chemistry and Biology 10, 2796-2804 (2010). PMID: 20820485, PMCID: pending
- Elman, N. M., Daniel, K., Jalali-Yazdi, F. & Cima, M. J., Super permeable nano-channel membranes defined with laser interferometric lithography. Microfluidics and Nanofluidics 8, 557-563 (2010). DOI: 10.1007/s10404-009-0537-z, PMID: N/A, PMCID: pending
- Elman, N.M., Masi, B.C., et al (2010) Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical- Systems. Lab on a Chip – Miniaturization for Chemistry and Biology, 10 (20), pp. 2796-2804.
- Brown, K.A., et al (2010) Scaling of transverse nuclear magnetic relaxation due to magnetic nanoparticle aggregation. Journal of Magnetism and Magnetic Materials, 322 (20), pp. 3122-3126.
- Ling, Y., Vassiliou, C.C., Cima, M.J. (2010) Magnetic relaxation-based platform for multiplexed assays. Analyst, 135 (9), pp. 2360-2364.
- Tobias, I.S., et al (2010) Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device. Journal of Controlled Release, 146 (3), pp. 356-362.
- Elman, N.M., Daniel, K., et al (2010) Super permeable nano-channel membranes defined with laser interferometric lithography. Microfluidics and Nanofluidics, 8 (4), pp. 557-563.
2009
- Daniel, K., Kim G. Y., Vassiliou, C. C., Galindo, M., Guimaraes, A. R., Weissleder, R., Charest, A., Langer, R., Cima, M. J. Implantable diagnostic device for cancer monitoring. Biosensors and Bioelectronics, 2009 24(11):3252-3257. DOI: 10.1016/j.bios.2009.04.010
2003
- Richards Grayson, A. C., I. S. Choi, et al. (2003). “Multi-pulse drug delivery from a resorbable polymeric microchip device.” Nat Mater 2(11): 767-772. PMID: 14619935
1999
- Santini, J. T., M. J. Cima, et al. (1999). “A controlled-release microchip.” Nature Biotechnology 397: 335-338. PMID: 9988626
1992
- McIntyre, P.C., Cima, M.J., Smith Jr., J.A. Effect of growth conditions on the properties and morphology of chemically derived epitaxial thin films of Ba2YCu3O7-x on (001)LaAlO3. Journal of Applied Physics, Feb 1992, Vol. 71, p1868-1877. DOI: 10.1063/1.351172
- Cima, M.J., Flemings, M.C., Figueredo, A.M. Semisolid solidification of high temperature superconducting oxides. Journal of Applied Physics, Jul 1992, Vol. 72, p179-190. DOI: 10.1063/1.352155