Publications

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2015

  • Li, M., Vassiliou, C.C., Colucci, L.A., Cima, M.J. 1H nuclear magnetic resonance (NMR) as a tool to measure dehydration in mice. NMR in Biomedicine, Aug 2015, Vol. 28, Issue 8, p1031-1039. ISSN: 09523480

  • Li, M., Cima, M.J., Milner Jr., D.A. If It's Not One Thing, It's Another: An Inverse Relationship of Malignancy and Atherosclerotic Disease. PLoS ONE, May 2015, Vol. 10 (5), p1-12. DOI: 10.1371/journal.pone.0126855

  • C. C. Vassiliou, V. H. Liu, M. J. Cima, Miniaturized, biopsy-implantable chemical sensor with wireless, magnetic resonance readout, Lab on a Chip, 2015, DOI: 10.1039/C5LC00546A

2014

  • Tavassolian N, Li M, Vassilou CC, Cima MJ, A Novel Magnetic Relaxation-Based Platform for Hydration Monitoring, IEEE Sensors Journal, 2014.
  • Liu VH, Vassiliou CC, Imaad SM, and Cima MJ; Solid MRI contrast agents for long-term, quantitative in vivo oxygen sensing, to be published Proceedings of the National Academy of Sciences, Volume 111, Number 18. (2014)
  • Cima MJ, Lee H, Daniel K, Tanenbaum LM, Mantzavinou A, Spencer KC, Ong Q, Sy JC, Santini J Jr, Schoellhammer CM, Blankschtein D, Langer RS. Single compartment drug delivery. Journal of Controlled Release. 2014;190:157-71. PMID: 24798478, PMCID: PMC4179298.

2013

  • Upadhyay, U.M., Tyler, B., Patta, Y., Wicks R., Spencer, K., Scott, A., Masi, B., Hwang, L., Grossman, R., Cima, M., Brem, H., Langer, R. Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain. Proc Natl Acad Sci. 2013; 11(45):16071-76. DOI: 10.1073/pnas.1313420110

2012

  • Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ. Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model. Biomaterials. 2012;33(23):5768-75. PMID: 22591609, PMCID: pending
  • Farra R, Sheppard NF, Jr., McCabe L, Neer RM, Anderson JM, Santini JT, Jr., Cima MJ, Langer R. First-in-human testing of a wirelessly controlled drug delivery microchip. Science translational medicine. 2012;4(122):122ra21. PMID: 22344516, PMCID: pending

2011

  • Y. Ling, M.J. Cima, Implantable Magnetic Relaxation Sensors for the Detection of Cardiac Biomarkers, Nature Biotechnology. 2011;29(3):273-7. PMID: 21317907, PMCID: pending
  • Scott, A. W., Tyler, B. M., Masi, B. C., Upadhyay, U. M., Patta, Y. R., Grossman, R., Basaldella, L., Langer, R. S., Brem, H. & Cima, M. J., Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials. 2011;32(10):2532-9. PMID: 21220172, PMCID: pending
  • Cima, M. J. (2011). "Microsystem Technologies for Medical Applications." Annual Review of Chemical and Biomolecular Engineering 2(1): 355-378. PMID: 22432623, PMCID: pending
  • Ling, Y., et al (2011) Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers. Nature Biotechnology, Article in Press.
  • Lee, H., Cima, M.J., (2011) An intravesical device for the sustained delivery of lidocaine to the bladder. Journal of Controlled Release, 149 (2), pp. 133-139.
  • Scott, A.W., et al (2011) Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model. Biomaterials, 2011.

2010

  • Lee, H. & Cima, M. J., An intravesical device for the sustained delivery of lidocaine to the bladder. Journal of Controlled Release. 2010;149(2):133-9. PMID: 20971144, PMCID: pending
  • Elman, N. M., Masi, B. C., Cima, M. J. & Langer, R., Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical-Systems. Lab on a Chip - Miniaturisation for Chemistry and Biology 10, 2796-2804 (2010). PMID: 20820485, PMCID: pending
  • This work describes different parameters associated with metal membranes used in drug delivery microchips.  This paper identified different membrane designs that were suitable for use in the microchips device.
  • Elman, N. M., Daniel, K., Jalali-Yazdi, F. & Cima, M. J., Super permeable nano-channel membranes defined with laser interferometric lithography. Microfluidics and Nanofluidics 8, 557-563 (2010). DOI: 10.1007/s10404-009-0537-z, PMID: N/A, PMCID: pending
  • Elman, N.M., Masi, B.C., et al (2010) Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on Micro-Electro-Mechanical- Systems. Lab on a Chip - Miniaturization for Chemistry and Biology, 10 (20), pp. 2796-2804.
  • Brown, K.A., et al (2010) Scaling of transverse nuclear magnetic relaxation due to magnetic nanoparticle aggregation. Journal of Magnetism and Magnetic Materials, 322 (20), pp. 3122-3126.
  • Ling, Y., Vassiliou, C.C., Cima, M.J. (2010) Magnetic relaxation-based platform for multiplexed assays. Analyst, 135 (9), pp. 2360-2364.
  • Tobias, I.S., et al (2010) Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device. Journal of Controlled Release, 146 (3), pp. 356-362.
  • Elman, N.M., Daniel, K., et al (2010) Super permeable nano-channel membranes defined with laser interferometric lithography. Microfluidics and Nanofluidics, 8 (4), pp. 557-563.

2009

  • Daniel, K., Kim G. Y., Vassiliou, C. C., Galindo, M., Guimaraes, A. R., Weissleder, R., Charest, A., Langer, R., Cima, M. J. Implantable diagnostic device for cancer monitoring. Biosensors and Bioelectronics, 2009 24(11):3252-3257. DOI: 10.1016/j.bios.2009.04.010

2003

  • Richards Grayson, A. C., I. S. Choi, et al. (2003). "Multi-pulse drug delivery from a resorbable polymeric microchip device." Nat Mater 2(11): 767-772. PMID: 14619935

1999

  • Santini, J. T., M. J. Cima, et al. (1999). "A controlled-release microchip." Nature Biotechnology 397: 335-338. PMID: 9988626

1992

  • McIntyre, P.C., Cima, M.J., Smith Jr., J.A. Effect of growth conditions on the properties and morphology of chemically derived epitaxial thin films of Ba2YCu3O7-x on (001)LaAlO3. Journal of Applied Physics, Feb 1992, Vol. 71, p1868-1877. DOI: 10.1063/1.351172
  • Cima, M.J., Flemings, M.C., Figueredo, A.M. Semisolid solidification of high temperature superconducting oxides. Journal of Applied Physics, Jul 1992, Vol. 72, p179-190. DOI: 10.1063/1.352155

1990

  • McIntyre, P.C., Cima, M.J., Ng, M.F. Metalorganic deposition of high-Jc Ba2YCu3O7-x thin films from trifluoroacetate precursors onto (100)SrTiO3. Journal of Applied Physics, Oct 1990, Vol. 68, p4183-4187. DOI: 10.1063/1.346233